Meetings and Events

GUM Online-Workshops 2021

1st Session – Genotoxic carcinogens
15.03.2020, 10 a.m. - 1 p.m. (CET)

Keynote speakers:

Andrea Hartwig (Karlsruhe Institute of Technology, Karlsruhe, GER)
Mode of action-based risk assessment of genotoxic carcinogens – results of a MAK/SKLM working group

Melanie Esselen (University of Münster, Münster, GER)
Natural genotoxins in food and food products – a challenge for risk assessment

Margherita Bignami (EFSA, Parma, ITA)
Genotoxic carcinogens as food contaminants: role of the mode of action in risk assessment

Additionally, two speakers will be selected from submitted abstracts.

2nd Session – Advanced in vitro models
18.03.2020, 3 - 6 p.m. (CET)

Keynote speakers:

Barbara Rothen-Rutishauser (Adolphe Merkle Institute – Fribourg, CH)
Predictive lung tissue models to assess the hazard of aerosols

Thomas Hartung (Johns Hopkins Bloomberg School of Public Health, Baltimore, USA)
Advancing cell culture from microphysiological to micropathopysiological systems

Stefan Pfuhler (Procter & Gamble, Cincinnati, USA)
Non-animal models that can be used to follow-up on positive results from the standard genotoxicity testing battery – an overview of recent progress of the Cosmetics Europe program

Additionally, two speakers will be selected from submitted abstracts.

3rd Session – Industrial Genotoxicity (Organized by the new GUM-IGG)
25.03.2020, 3-6 p.m. (CET)


Lea A. l. Vaas (Bayer AG, Berlin, GER), Andreas Zeller (F. Hoffmann – La Roche Ltd, Basel, CH)
Statistical evaluation of the flow cytometric micronucleus in vitro test – same but different

Birgit Mertens (Sciensano, Brussels, BE) & Paul White (Health Canada, Ottawa, CA)
An update on the OECD assessment of miniaturized Ames assays

Giel Hendriks (Leiden University Medical Centre, Leiden, NL) & Steven Bryce (Litron Laboratories, New York City, USA),
ToxTracker/Multiflow: An update on mechanistic/screening assays and their applications

Roland Froetschl (Federal Institute for Drugs and Medical Devices, Bonn, GER) & Andreas Czich (Sanofi, Frankfurt, GER)
N-nitroso impurities in sartans and other drugs

Carol Beevers (Exponent Inc.) & Jasmin Lott (Boehringer Ingelheim)
Consideration of Criteria used for Dose Selection and defining the MTD for in vivo Follow Up Studies: Impact and Regulatory Acceptance

The event is free of charge and GUM members as well as non-members are kindly invited to join. In case you want to register please contact Julia Bornhorst ( in order to receive the registration form. Registration is possible until 26 of February.